منابع مشابه
Galectin-1 in myelin repair
Galectin-1 (Gal-1) is a member of a highly conserved family of animal lectins which binds to the common disaccharide [Galβ(1-4)-GlcNAc] on both Nand O-glycans decorating cell surface glycoconjugates. Current evidence supports a role for Gal-1 in the pathophysiology of multiple sclerosis (MS), one of the most prevalent chronic inflammatory diseases, as approximately one third of MS patients gene...
متن کاملMyelin Repair Foundation
The Myelin Repair Foundation is pleased to present this annual review of our progress toward achieving our goal of discovering and validating effective new treatment targets for multiple sclerosis. We were extremely pleased by the rapid progress of the team both in advancing frontiers of translational scientific research and demonstrating the power of the MRF Accelerated Research CollaborationT...
متن کاملMyelin Repair Foundation
• Creating new purification and culture techniques for neural cells, • Making new antibodies to visualize protein distribution or control signaling between cells, • Constructing new interfering RNAs and breeding transgenic animals to control gene expression and protein production • Developing new models to study biological mechanisms and evaluate therapeutic effects in cell culture, animal mode...
متن کاملTriggering the regeneration and tissue repair programs.
In early October 2008, researchers from diverse backgrounds gathered at an EMBO conference entitled 'The Molecular and Cellular Basis of Regeneration and Tissue Repair' to discuss the basic biology of regeneration. Topics included cell plasticity in regenerative and developmental contexts, and the link between wound healing and regeneration. The meeting also highlighted the progress made in ide...
متن کاملMyelin Repair Foundation Archived Research Summaries
Scientific Summary: CD11c DCs play a major role in both the initiation and progression of autoimmune inflammatory disease in the CNS. Since the CNS serves as the primary site where activation of pathogenic Th1/Th17 cells specific for endogenous myelin epitopes (i.e., epitope spreading), which play a critical role in driving progressive autoimmune disease, the current data suggests that the infl...
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ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2010
ISSN: 1945-3477
DOI: 10.1038/scibx.2010.912